Coverage of Lazio v Celtic in the Group E match from Stadio Olimpico
Coverage of Middlesbrough v Preston North End in the Championship match at Riverside Stadium
Coverage of the Group G match from Etihad Stadium, as the current champions look to finish top of the group with victory in this meeting. Two late goals from Julian Alvarez and Jeremy Doku gave City a 3-1 victory in the reverse fixture back in October, as Pep Guardiola's side equalled the record for the longest European unbeaten run by an English club
Coverage of Paris Saint-Germain v Newcastle United in the Group F match from Parc des Princes
Coverage of Watford v Norwich City in the Championship match at Vicarage Road
Coverage of Galatasaray v Manchester United in the Group A match from RAMS Park
Coverage of Ipswich Town v Millwall in the Championship match at Portman Road
Coverage of the Group B match from Emirates Stadium, as Mikel Arteta's side look for the victory that would get them through to the last 16, as well as confirming them as group winners. The reverse fixture saw the French side come from behind to win 2-1, with goals from Adrien Thomasson and Elye Wahi cancelling out Gabriel Jesus' opener
All the action from the second-round tie at LNER Community Stadium. Wigan lifted the trophy in 2013, overcoming Manchester City in the final, but have struggled for consistency in League One so far this season and face a potentially tricky test against non-league opposition who will be keen to impress and earn an even bigger tie in the next round. National League York City beat Chester 2-1 in a replay in the last round to reach this stage, and are looking to reach the third round for the first time since the 2010/11 season
Coverage of Harlequins v Sale Sharks in the match from Twickenham Stoop
Coverage of the Championship match at Deepdale, as two teams at opposite ends of the table go head to head. The visitors are struggling in the relegation zone, having won only two of their opening 16 matches, while the hosts are pushing for a play-off place in a tightly contested top-half of the table